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News about Sirtuin and HD

Posted by sarmiento 
News about Sirtuin and HD
December 21, 2011 05:29PM
SIRT1 slow HD in mousemodel. They wrote "dramatically delay" which sounds good.
[www.medicalnewstoday.com]
SIRT1 get activated by Grapeseedextract, Resveratrol?
Seems to be a good supplement .



Edited 1 time(s). Last edit at 12/21/2011 06:27PM by sarmiento.
Re: News about Sirtuin and HD
December 21, 2011 07:12PM
Here's what's interesting about this - there is a SIRT1 inhibitor in clinical trials for HD in Europe.
Re: News about Sirtuin and HD
December 21, 2011 10:30PM
SIRT1 activation is a known promoter of autophagy and this is the likely mechanism that delays HD progression.
Re: News about Sirtuin and HD
December 23, 2011 07:12PM
Here's a link to more info about the European trial and the logic behind inhibiting SIRT1.

[www.hdsa.org]
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