The mission of the HDLighthouse Families Web site is to present and explain the latest research findings so that HD families can become proactive in their care, have hope for the future, and make good decisions in the present.  Additionally we provide information that is vital to the the support of HD families.  Where possible we will direct you to specialists in the your area of concern, but if we are able to provide better information then you'll find it here.

Invitation to participate in a quality of life survey

This was first announced latest last year, but it's still open - so if you haven't responded yet please do it now!

Welcome to HDLF

First, I'd like to thank you for visiting HDLF and I hope your experience here is a good one.  We created this new site to combine the best features of HDAC.org and HDLighthouse.org and we hope that you enjoy the results.

I'm Steve Ireland and I'm the site designer and developer.  Marsha Miller is the site editor and content queen.  Since content is everything then her articles are what make the site what it is.

Neurosearch Amends the ACR-16 Results

The press release below involves a correction to previously announced results of the Huntexil (ACR16) clinical trial in Europe.

Cargo Recognition is Impaired in HD

Autophagy increases but is impaired, leading to an increase of the HD protein in the cytosol.

CoQ10 and Minocycline not helpful in Mouse Model

Neither CoQ10 nor minocycline were helpful in the R6/2 mouse and high doses of minocycline resulted in decreased survival time.

The European trial of ACR16 yields good results

ACR16 improves voluntary and involuntary movement. This is wonderful news!

Synaptic activity, aggregation, and memantine

This is a landmark study because it brings together and adds to previous research and points to a potentially significant treatment.

Coalition researcher Dr. Michael R. Hayden teamed up with Dr. Stuart Lipton,

An Interview with Dr. Jan Nolta

A trial of mesenchymal stem cell is planned for the end of 2010.

Mesenchymal Stem Cells Repair Neurotoxin Damage in an Animal Model

Preclinical work supports the use of mesenchymal stem cells to treat neurodegenerative disorders.

Cogane

A new BDNF inducer enters the pipeline.

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