Yes, the CoQ10 is what I'm excited about. The results of the CARE-HD study, which involved Remacemide and CoQ10 are due out in about two months. My guess is that if CoQ10 is effective in slowing HD progress, it is going to be a modest effect. But any effect is good news because it buys time. And it would be very significant because CoQ10 delays onset and slows progress in the HD mice. If it does the same for people, this would be confirmation that we are right to be excited about all the new research findings.- CoQ10, creatine, minocycline, and EPA all delay onset and progress in the mice. Clinical trials in people are starting for the last three.
I think the neurotrophic factor research sounds very promising too.
I always attend the research workshops at the conventions and I also attended a Thanksgiving dinner for HD researchers. They really are very enthusiastic at the progress being made. One of them, whom I noticed was more cautious in her optimism the first time I met her in 1998, has said that the progress from the lab to clinical trials is proceding much faster than she had expected.
I wrote an essay about reasons for hope. [
www.hdac.org]