The sole reason RG6042 (IONIS-HTTRx) is not being administered to HD victims in the advanced stage, when degeneration is not only severe but accelerating, is that Roche (Genentech) has a responsibility to protect its stockholders from unethical litigation by the lawyers of patients who, despite having signed liability waivers protecting all parties involved in saving their lives, may neverthelessby jabowery - Huntington's Disease Support Center
As of June 1, Public Law No: 115-176 makes it legal to treat Huntington's victims with the gene silencing therapy, IONIS-HTTRx. The Huntington's Disease Society of America appears uninterested*. So I've been searching in vain for any indication that some organization may be attempting to negotiate the terms with Roche Pharmaceuticals, the owner of the IONIS-HTTRx patent, to supply neurologisby jabowery - Huntington's Disease Support Center
My wife, Jan has HD and has started complaining of numbness in her legs -- at times when she is standing. She's at a stage where she no longer qualifies for clinical trials because of her low total function. She has difficulty being understood when she speaks. Since this numbness is not alleviated by standing I'm wondering if she might have a form of repetitive motion disorder resulting froby jabowery - Huntington's Disease Support Center
I am the only caregiver for my wife and she is no longer capable of being left alone. I'm going under the knife and will be totally incapacitated for 24 hours after they are discharging me from the hospital (its Medicaid rules) and then partially incapacitated for up to a month with the loss of the use of my left arm. (Fortunately my right arm is my favored arm.) Needless to say, I have no cby jabowery - Huntington's Disease Support Center
"The patients, however, had an earlier elevation of HGH than the controls...The patients, although awake, ceased to have choreiform movements for at least the last 60 minutes of the insulin tolerance tests." Yes, I know that "correlation doesn't imply causation" but then neither does correlation imply lack of causation. This is the reason clinical trials are conducted:by jabowery - Huntington's Disease Support Center