I had a few issues to overcome on Tuesday, but I was accepted into the Selisistat study. I'm on the drug now in my 4th day of 14 total. The only side effect so far is a feeling of lightheadedness and weakness for a couple of hours after each dose. I was surprised at the size of the pill - it's just a little larger than an aspirin.

I'll write a detailed report for the forum after I finish. I was glad to see that my skin didn't turn green and I'm not growing a new nose on my forehead. :-) I can imagine billions of little nano guys with machetes attacking my cells to cut out the mutant htt and leave the good stuff. That's what it's supposed to do. This study is scheduled to end in August and a Phase 2 trial should start sometime after that. Europe is ahead of us - they already have a Phase 2 trial going on.

Will

Great news! Maybe my mother can participate in the Netherlands!

Will, you are amazing! Keep us posted! (especially if you start turning green)

Carla

Great going Will. You are an inspiration.
Mike

Thanks for participating Will.

Hi Will

That's great news. What is the study hoping to achieve? Please say a cure? I tried to find out online.....

Thanks

Existing drug therapies can treat some the symptoms but selisistat is the first drug designed to help the patient’s body break down these ‘bad’ proteins so they can be disposed of more easily.

This I found on the internet!

I just finished the study today. I wrote a detailed report about the whole experience. If Marsha will PM me her e-mail, I'll send it to her so she can post it on the site. Marsha - I seem to have lost yours. Thanks!

Will

Will, I wouldn't mind reading your long post right here! It is so nice to see such positive & promising news, and it's not surprising that Will is participating & sharing it. Good for you, Will. And thank you. Both for the good you're doing with your participation in this & other things + for being such a positive voice in this forum.

How is your foot from the surgery, by the way?

Will,

Just returned from our first visit to Wake Forest to enroll my husband in the Siena study~ we will know in a few days if he gets in~
Hope he has postitive results once he starts the med.

Thanks for all you do
Ladyluck

Will- I'm a bit late in responding. . but this is such great news. I am so happy for you. We can always count on you for a smile Am looking forward to hearing about it.