Basic Research

An Interview with Dr. Jan Nolta

A trial of mesenchymal stem cell is planned for the end of 2010.

Mesenchymal Stem Cells Repair Neurotoxin Damage in an Animal Model

Preclinical work supports the use of mesenchymal stem cells to treat neurodegenerative disorders.

Cogane

A new BDNF inducer enters the pipeline.

The Search for Genetic Modifiers

The search for genetic modifiers is an important part of the effort to find treatments.

The RCAN1 gene and HD

Overexpression of the RCAN1 gene may be a treatment for Huntington's Disease.

Axonal Transport Impaired in HD

Researchers have identified the mechanism by which axonal transport is impaired in neurons in HD.

Rhes and the HD protein

Researchers at Johns Hopkins have discovered that a protein called rhes binds to the HD protein and causes toxicity

The RCAN1 gene and HD

Overexpression of the RCAN1 gene may be a treatment for Huntington's Disease.

Acetylation of the HD protein

MSG-MIND researchers discover a new therapeutic target: increased acetylation enhances clearance of the HD ptotein from the nucleus.

Toxic HD protein fragments

Research continues to support the toxic fragment hypothesis.
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