The Search for Genetic Modifiers
Submitted by Marsha Miller Ph.D. on Sun, 12/06/2009
The search for genetic modifiers is an important part of the effort to find treatments.
Gene Transcription
The RCAN1 gene and HD
Submitted by Marsha Miller Ph.D. on Sun, 12/06/2009
Overexpression of the RCAN1 gene may be a treatment for Huntington's Disease.
The RCAN1 gene and HD
Submitted by Marsha Miller Ph.D. on Sat, 07/04/2009
Overexpression of the RCAN1 gene may be a treatment for Huntington's Disease.
The HD protein activates Nrf-2 responsive genes
Submitted by Marsha Miller Ph.D. on Mon, 12/08/2008
A cell model study tells us more about the dysregulation of gene transcription in HD.
Altered histone monoubiquitylation and transcriptional dysregulation
Submitted by Marsha Miller Ph.D. on Sat, 07/19/2008
MIND researchers discover new insights into transcriptional dysregulation in HD.
Early neurotransmitter problems in HD
Submitted by Marsha Miller Ph.D. on Fri, 03/28/2008
In a fruitfly model, the HD protein causes early synaptic problems which can be addressed through the genes which regulate calcium channels.
