Gene Transcription

The Search for Genetic Modifiers

The search for genetic modifiers is an important part of the effort to find treatments.

The RCAN1 gene and HD

Overexpression of the RCAN1 gene may be a treatment for Huntington's Disease.

The RCAN1 gene and HD

Overexpression of the RCAN1 gene may be a treatment for Huntington's Disease.

The HD protein activates Nrf-2 responsive genes

A cell model study tells us more about the dysregulation of gene transcription in HD.

Altered histone monoubiquitylation and transcriptional dysregulation

MIND researchers discover new insights into transcriptional dysregulation in HD.

Early neurotransmitter problems in HD

In a fruitfly model, the HD protein causes early synaptic problems which can be addressed through the genes which regulate calcium channels.
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