Hi, I think the guy at the Twitter profile below used to run this site. You might try contacting him to find out what's going on with the site. Ericby EricR - Huntington's Disease Support Center
Here's a link to the publication you are looking for:by EricR - Huntington's Disease Support Center
Here's a recent interview with Dr Wahls. She talks about her protocol, clinical trials and some general results from patients who use her protocol.by EricR - Huntington's Disease Support Center
Link to article: Article text: Strict eating schedule can lower Huntington disease protein in mice Huntington disease (HD) is an inherited, progressive disorder that causes involuntary movements and psychiatric problems. Symptoms appear in adulthood and worsen over time. Children born to a parent with HD have a one in two chance of inheriting the disease, which is caused by a buildupby EricR - Huntington's Disease Support Center
Original article is here: Ionis drug for Huntington's disease shows early signs of effectiveness An experimental drug from Ionis Pharmaceuticals safely reduced a toxic brain protein in Huntington’s disease, according to early results in patients. This gives promise that the drug may halt or even reverse the fatal genetic disease, which has never been done. Based on earlier research,by EricR - Huntington's Disease Support Center
Dr. Bredesen has published a book called "The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline". Here's a link to Amazon's product page: Also, here's another presentation by Dr. Bredesen:by EricR - Huntington's Disease Support Center
Maybe this?by EricR - Huntington's Disease Support Center
Swanson trehalose is cheaper when purchased directly from Swanson. Here's a link:by EricR - Huntington's Disease Support Center
Pete, Here's a link to a study that says too much (3 mg) melatonin can cause a "hangover" effect during the day. The study found that a 0.3 mg dosage was enough to help the test subjects sleep through the night. Here's a product that has 0.3 mg (300 micrograms) dose: Ericby EricR - Huntington's Disease Support Center
I read the Nuvigil website. Nuvigil is not designed to help you sleep. It looks like it used to keep you awake when you are very sleepy. From the website: "NUVIGIL is a prescription medicine used to improve wakefulness in adults who are very sleepy due to one of the following diagnosed sleep disorders: " sleep apnea, narcolepsy, or shift work sleep disorder. "NUVIGILby EricR - Huntington's Disease Support Center
When I google "melatonin brittle bones" the top hits are about how melatonin may help or prevent osteoporosis. For example here's an article called "Melatonin makes old bones stronger, research shows": Also you might want to take a look at the article I linked to previously called "Melatonin treatment success in HD mice"by EricR - Huntington's Disease Support Center
Look into melatonin. In addition to helping with sleep it may also have a positive effect on the disease process. Here's an article about this:by EricR - Huntington's Disease Support Center
The Today Show recently reported on this: 3/2/2017: edited to add link to Today Show website. Previously was linked to a youtube video that was taken down.by EricR - Huntington's Disease Support Center
Here's some interesting information that I want to pass along. It's a about a small trial (10 patients) of a program to try to reverse cognitive decline in Alzheimer's patients. I think the principles involved may also apply to HD. Article: The interventions (from the article): Video presentation by the doctor: This is the abstract from the article: This report describy EricR - Huntington's Disease Support Center
I think this is the full link:by EricR - Huntington's Disease Support Center
Look into melatonin. In additional to helping with sleep it may also have a positive effect on the disease process. Here's an article about this: Ericby EricR - Huntington's Disease Support Center
The key point I see in the article is: "Reducing mTORC1 activation either through drugs or low-protein foods may have a positive influence on preventing the disease process," I found a study that says consuming milk MAY increase mTORC1 activation. Here's an excerpt from the abstract: "Whereas human breast milk is the ideal food for infants allowing appropriate postnatal growby EricR - Huntington's Disease Support Center
For reference, I think this is the article Waz1980 is talking about:by EricR - Huntington's Disease Support Center
Here are a couple of links if you want to read more about this. Maybe HD researchers can learn from this. Press release from the company developing the treatment: Information about the treatment:by EricR - Huntington's Disease Support Center
Hi Barb, Here's the reason I posted this: Dr Walsh has had success in treating psychiatric problems by diagnosing and treating nutrient imbalances. I'm suggesting to anyone reading this that they might want to look into Dr. Walsh's research as a way to treat the psychiatric issues associated with HD. As a starting point they can read the book excerpts and listen to the interview. Theby EricR - Huntington's Disease Support Center
I came across this book called "Nutrient Power: Heal Your Biochemistry and Heal Your Brain" by Dr William J Walsh. I read the book preview on Amazon and listened to an interview with Dr Walsh. I'm wondering whether the principles he describes might be useful for treating the symptoms of HD. I copied the preface of the book and an excerpt of chapter 1 below. Here's a link to the bookby EricR - Huntington's Disease Support Center
Trial details from Prana. Both links have similar information. Presentation style: Text version:by EricR - Huntington's Disease Support Center
Maybe the results of these studies can be used to derive a treatment for HD. Parkinson's study: Oculopharyngeal Muscular Dystrophy study:by EricR - Huntington's Disease Support Center
Hi Pete, I don't have any experience or additional info. Ericby EricR - Huntington's Disease Support Center
I want to point out that there is a relatively new form of creatine available that requires a much smaller dose to get the same results and also has less side effects. It's called creatine hydrochloride. You can read more about it on these vendor sites:by EricR - Huntington's Disease Support Center
Charity Navigator has some stats:by EricR - Huntington's Disease Support Center
bothfeet Wrote: ------------------------------------------------------- > could someone explain all that in simpler terms > please , They a have short video that explains how it works.by EricR - Huntington's Disease Support Center
Update: trial results expected early next year. From a Prana press release: The Reach 2HD trial is a six month double-blind placebo controlled Phase 2 trial on 109 early-to-mid stage Huntington’s disease patients. The trial was successfully completed at the end of July 2013 with 95% of participants completing the entire six months of treatment. There has been a delay in finalising the daby EricR - Huntington's Disease Support Center
There is a press release on Prana's website dated 7/23/2013. Here are the details: --- Prana Completes Phase 2 Huntington Disease Trial with PBT2 Prana Biotechnology today announced the successful completion of Reach2HD, a phase 2 clinical trial in patients with early to mid-stage Huntington disease. The Company expects to announce the results arising from the trial in October. Reach2by EricR - Huntington's Disease Support Center
In the abstract of the research paper "Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons" it states: "At the mechanistic level, trehalose treatment led to a drastic upregulation in the expression of key autophagy-related genes at the mRNA level including Lc3, Becn1, Sqstm1 and Atg5. Consistent with these changes, trehalose adby EricR - Huntington's Disease Support Center