NCAMs in the HD mice
Marsha L. Miller, Ph.D., Mar, 02/06/2007
Problems with NCAMs may explain cognitive and olfactory dysfunction in HD.
Basic Research
HSG Press Conference - January 2007
Marsha Miller, Ph.D., Dom, 02/04/2007
Members of the Huntington Study Group held their quarterly press conference with Huntington’s Disease family reporters.
Molecular Zipcodes Provide Address for HD Protein
Marsha L. Miller, Ph.D., Vie, 02/02/2007
New findings based on new technology show that the HD protein is being misdirected within the cell. Small molecules are being developed which might place a 'molecular zip code' on the problem.
Stem Cells and The Aging Brain
Marsha L. Miller, Ph.D., Mar, 12/19/2006
Stem cells are still present in the middle aged brain; they just aren't dividing.
ReNeuron Files Application with FDA to Begin Phase I Study of Stem Cell Treatment for Stroke Patients.
Marsha L. Miller, Ph.D., Vie, 12/08/2006
A company currently doing stem cell research in animal models of HD, has filed an application with the FDA for permission to begin clinical trials of stem cell treatments for stroke victims.
Overexpressing Normal Huntington's Slightly Beneficial in a Mouse Model
Marsha L. Miller, Ph.D., Jue, 12/07/2006
A study with YAC128 mice suggests that overexpression of the normal huntingtin's protein is not enough to counteract all the negative effects of the HD protein.
Ampakines and HD
Malcolm Casale, Ph.D., Sáb, 09/09/2006
Ampakines may become a treatment for HD in the next few years.
Hereditary Disease Foundation meeting: HD 2006: Changes, Advances and Good News (CAG)n
Marsha Miller, Ph.D., Sáb, 08/26/2006
We were invited to attend this year?s meeting of the Hereditary Disease Foundation to learn about the progress being made and to share the broad findings with other HD family members. There were 350
Mice Engineered Without CAG Repeats
Marsha Miller, Ph.D., Mar, 07/18/2006
Mice engineered without CAG repeats are normal when born but develop cognitive deficits later on.
Participating in the PREDICT-HD Study
Will Brown, Sáb, 07/08/2006
Will is a participant in the PREDICT-HD study. His experiences in the study are entertaining as well as enlightening.
