Problems with NCAMs may explain cognitive and olfactory dysfunction in HD.
Members of the Huntington Study Group held their quarterly press conference with Huntington’s Disease family reporters.
New findings based on new technology show that the HD protein is being misdirected within the cell. Small molecules are being developed which might place a 'molecular zip code' on the problem.
Stem cells are still present in the middle aged brain; they just aren't dividing.
A company currently doing stem cell research in animal models of HD, has filed an application with the FDA for permission to begin clinical trials of stem cell treatments for stroke victims.
A study with YAC128 mice suggests that overexpression of the normal huntingtin's protein is not enough to counteract all the negative effects of the HD protein.
Ampakines may become a treatment for HD in the next few years.
We were invited to attend this year?s meeting of the Hereditary Disease Foundation to learn about the progress being made and to share the broad findings with other HD family members. There were 350
Mice engineered without CAG repeats are normal when born but develop cognitive deficits later on.
Will is a participant in the PREDICT-HD study. His experiences in the study are entertaining as well as enlightening.