2008 CHDI HD Therapeutics Conference: A Report from an HD Family Perspective
Jim Tretheway, HD family member, Dom, 02/24/2008
Progress continues with CHDI's strategic efforts to develop treatments for Huntington's Disease.
Basic Research
The Predict-HD Study Identifies Early Changes
Marsha L. Miller, Ph.D., Mar, 01/01/2008
The Predict-HD study has identified early, subtle, measurable changes that take place 10-20 years before diagnosis.
Lack of BDNF and overeating
Marsha L. Miller, Ph.D., Sáb, 12/29/2007
A loss of BDNF in adult mice leads to overeating and obesity.
Does the huntingtin protein play a role in autophagy?
Marsha L. Miller, Ph.D., Jue, 11/08/2007
Boosting BDNF by Listening to Music
Marsha L. Miller, Ph.D., Dom, 10/07/2007
Normal mice exposed to music have an increase in BDNF in the hippocampus.
BDNF, fragile X syndrome, and memory
Marsha L. Miller, Ph.D., Dom, 10/07/2007
Researchers restored the capacity to retain new memories in fragile X syndrome mice by infusing BDNF to the hippocampus region.
Press release for the BDNF neurogenesis study.
Marsha L. Miller, Ph.D., Mié, 09/26/2007
Neurogenesis in HD mice prolongs life
Marsha L. Miller, Ph.D., Sáb, 09/22/2007
In a landmark study, researchers administered BDNF and noggin and induced neurogenesis and prolonged life in the R6/2 mice.
RE1/NRSE Mediated Gene Transcription
Marsha L. Miller, Ph.D., Mié, 08/22/2007
New and exciting research at the University of Leeds unveils new opportunities for promising treatmentment for Huntington disease patients.
Gene Expression Analysis and Extra-Mitochondrial Energy Metabolism
Marsha L. Miller, Ph.D., Mié, 08/22/2007
The HD protein causes a depletion in cellular energy but not through direct effects on the mitochondria, the cell's energy factory.
