The Search for Genetic Modifiers
Enviado por Marsha Miller Ph.D. el Dom, 12/06/2009.
The search for genetic modifiers is an important part of the effort to find treatments.
Gene Transcription
The RCAN1 gene and HD
Enviado por Marsha Miller Ph.D. el Dom, 12/06/2009.
Overexpression of the RCAN1 gene may be a treatment for Huntington's Disease.
The RCAN1 gene and HD
Enviado por Marsha Miller Ph.D. el Sáb, 07/04/2009.
Overexpression of the RCAN1 gene may be a treatment for Huntington's Disease.
The HD protein activates Nrf-2 responsive genes
Enviado por Marsha Miller Ph.D. el Lun, 12/08/2008.
A cell model study tells us more about the dysregulation of gene transcription in HD.
Altered histone monoubiquitylation and transcriptional dysregulation
Enviado por Marsha Miller Ph.D. el Sáb, 07/19/2008.
MIND researchers discover new insights into transcriptional dysregulation in HD.
Early neurotransmitter problems in HD
Enviado por Marsha Miller Ph.D. el Vie, 03/28/2008.
In a fruitfly model, the HD protein causes early synaptic problems which can be addressed through the genes which regulate calcium channels.
